A Short History of Nearly Everything (ISBN 0-7679-0817-1) is a general science book by Bill Bryson, which explains some areas of science in ordinary language. It was the bestselling popular science book of 2005 in the UK, selling over 300,000 copies.

A Short History deviates from Bryson's popular travel book genre, instead describing general sciences such as chemistry, paleontology, astronomy, and particle physics. In it, he explores time from the Big Bang to the discovery of quantum mechanics, via evolution and geology.

Bryson tells the story of science through the stories of the people who made the discoveries, such as Edwin Hubble, Isaac Newton, and Albert Einstein.

Bryson describes graphically how big the universe is, and how small atoms and subatomic particles are. Furthermore, he reports on the likeliness of the Earth being struck by a meteor, how unlikely it is that humans will spot a meteor before it impacts the Earth, and the extensive damage that such an event would cause. He also explores the history of biology, botany, and zoology, and traces life from its first appearance all the way to today's modern humans, placing much emphasis on the development of the modern Homo sapiens. All along the book, humorous stories about the scientists behind the discovery and their half-crazy behaviour is given. Throughout the book, there are many reports on the way humans change the Earth's climate and destroy other species, as well how the Earth was and is a very destructive planet itself, briefly touching about earthquakes, volcanoes, tsunamis, hurricanes, and mass extinctions. His tendency to look for big explosions and awe-inspiring devastation takes him to the most destructive disasters in the history of the world, from Krakatoa to Yellowstone National Park.

Bryson ends the book by noting how many extinctions humans are responsible for, and how lucky mankind is to be living on planet Earth today.
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