Molecular Neurosurgery with Targeted Toxins
Humana Press | 1588291995 | Edition - 2005-03-22 | PDF | 328 pages | 3.2 MB | rapidshare&Megaupload


Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.
Downlaod From RapidSHare.com
http://rapidshare.com/files/62165126...ted_Toxins.rar
or
http://www.megaupload.com/?d=7VHIOYT2