A Multidisciplinary Approach to the Treatment of Early Colorectal Cancer

Product Description:
Colorectal cancer (CRC) is a major public health problem in the United States and
throughout the world. Each year, this disease affects nearly 150,000 new patients, and it is
the second leading cause of mortality, accounting for almost 50,000 deaths in the United
States. Worldwide, CRC affl icts nearly 800,000 individuals and is associated with 500,000
deaths. Over the past 10 years, signifi cant advances have been made in the screening for
and early detection of CRC as well as in the different treatment approaches—including
surgery, radiation therapy, and chemotherapy—that are now available for patients with
early-stage CRC and more advanced stages of the disease. Without question, CRC has now
become a highly preventable and curable disease through regular screenings and early
detection, and highly treatable when diagnosed at an even more advanced stage.
In this book, we have condensed and summarized a wealth of essential information on
the multidisciplinary treatment approach for patients with early-stage CRC, and presented
it in a practical and readable format. It is critical that a team of physicians from various
specialties—including surgery, radiation oncology, medical oncology, pathology, and radiology—
provide their particular expertise in developing individual treatment plans for
patients with CRC. With this in mind, the fi rst three chapters review various key aspects
relating to the surgical management of patients with CRC. The subsequent two chapters
are focused on pathologic staging and the role of prognostic and predictive biomarkers
in pathologic assessment. The fi nal three chapters are devoted to an update on the role
of adjuvant chemotherapy for colon cancer, the integration of biologic agents in adjuvant
treatment regimens, and the combined-modality approach to treating rectal cancer.
My hope is that this book will serve as a source of practical information that can be
used by physicians and other health-care professionals actively involved in the daily care
of patients with CRC. This book should be viewed as a work in progress; our hope is to
update it in the future to incorporate
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